In this conversation, Mark Solms explores the territory where neuroscience meets depth psychology, drawing on the neuropsychoanalytic research that has defined his career. He speaks to affective neuroscience and the basic emotional drives that shape human experience, the surprising role of joyful play in harmonizing human nature, and the biological and spiritual correlates of suffering and flourishing. Author of The Hidden Spring and editor of the revised Standard Edition of Freud’s complete works, he considers the forms consciousness takes and where he hopes the science of the feeling brain will go next.